SARS-CoV-2 Nsp15 suppresses type I interferon production by inhibiting IRF3 phosphorylation and nuclear translocation

SARS-CoV-2 Nsp15 suppresses type I interferon production by inhibiting IRF3 phosphorylation and nuclear translocation

Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes 2019 coronavirus disease (COVID-19), poses a significant threat to global public health security. Like other coronaviruses, SARS-CoV-2 has developed various strategies to inhibit the production of interferon (IFN). H...

Full description

Bibliographic Details
Main Authors: Dianqi Zhang, Likai Ji, Xu Chen, Yumin He, Yijie Sun, Li Ji, Tiancheng Zhang, Quan Shen, Xiaochun Wang, Yan Wang, Shixing Yang, Wen Zhang, Chenglin Zhou
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Immunology
Virology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223017820

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223017820

Similar Items