Developmental or adult-onset deletion of neurotensin receptor-1 from dopamine neurons differentially reduces body weight

Developmental or adult-onset deletion of neurotensin receptor-1 from dopamine neurons differentially reduces body weight

Central neurotensin signaling via neurotensin receptor-1 (NtsR1) modulates various aspects of physiology, including suppressing feeding and promoting locomotor activity that can support weight loss. However, it remains unclear when and where NtsR1 expression contributes to control of body weight vs....

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Bibliographic Details
Main Authors: Patricia Perez-Bonilla, Jariel Ramirez-Virella, Pooja Menon, Eva Troyano-Rodriguez, Sydney K. Arriaga, Anna Makela, Raluca Bugescu, Michael J. Beckstead, Gina M. Leinninger
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Neuroscience
Subjects:
ventral tegmental area (VTA)
feeding
locomotor activity
obesity
energy balance
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.874316/full

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https://www.frontiersin.org/articles/10.3389/fnins.2022.874316/full

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