Association study of germline variants in CCNB1 and CDK1 with breast cancer susceptibility, progression, and survival among Chinese Han women.

The CCNB1 and CDK1 genes encode the proteins of CyclinB1 and CDK1 respectively, which interact with each other and are involved in cell cycle regulation, centrosome duplication and chromosome segregation. This study aimed to investigate whether the genetic variants in these two genes may affect brea...

Full description

Bibliographic Details
Main Authors: Yan Li, Yi-Lin Chen, Yun-Tao Xie, Li-Yuan Zheng, Ji-Yuan Han, Hui Wang, Xin-Xia Tian, Wei-Gang Fang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873991?pdf=render