C60 fullerene and its nanocomplexes with anticancer drugs modulate circulating phagocyte functions and dramatically increase ROS generation in transformed monocytes

C60 fullerene and its nanocomplexes with anticancer drugs modulate circulating phagocyte functions and dramatically increase ROS generation in transformed monocytes

Abstract Background C60 fullerene-based nanoformulations are proposed to have a direct toxic effect on tumor cells. Previous investigations demonstrated that C60 fullerene used alone or being conjugated with chemotherapeutic agents possesses a potent anticancer activity. The main aim of this study w...

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Bibliographic Details
Main Authors: Larysa M. Skivka, Svitlana V. Prylutska, Mariia P. Rudyk, Nataliia M. Khranovska, Ievgeniia V. Opeida, Vasyl V. Hurmach, Yuriy I. Prylutskyy, Leonid F. Sukhodub, Uwe Ritter
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Cancer Nanotechnology
Subjects:
C60 fullerene
Anticancer drugs
Nanocomplexes
Transformed monocytes
ROS generation
Computer simulation
Online Access:http://link.springer.com/article/10.1186/s12645-017-0034-0

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http://link.springer.com/article/10.1186/s12645-017-0034-0

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