FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes

NMR experiments reveal distinct interactions of the histone chaperone, FACT, with the proximal and distal flexible histone H2A and H2B tails of the asymmetrically unwrapped nucleosome.

Bibliographic Details
Main Authors: Yasuo Tsunaka, Hideaki Ohtomo, Yoshifumi Nishimura
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03785-z