FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes
NMR experiments reveal distinct interactions of the histone chaperone, FACT, with the proximal and distal flexible histone H2A and H2B tails of the asymmetrically unwrapped nucleosome.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-08-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03785-z |
| _version_ | 1828154119459700736 |
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| author | Yasuo Tsunaka Hideaki Ohtomo Yoshifumi Nishimura |
| author_facet | Yasuo Tsunaka Hideaki Ohtomo Yoshifumi Nishimura |
| author_sort | Yasuo Tsunaka |
| collection | DOAJ |
| description | NMR experiments reveal distinct interactions of the histone chaperone, FACT, with the proximal and distal flexible histone H2A and H2B tails of the asymmetrically unwrapped nucleosome. |
| first_indexed | 2024-04-11T22:35:46Z |
| format | Article |
| id | doaj.art-6570ec0aa81747968db9acc4684cc181 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-11T22:35:46Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-6570ec0aa81747968db9acc4684cc1812022-12-22T03:59:13ZengNature PortfolioCommunications Biology2399-36422022-08-015111410.1038/s42003-022-03785-zFACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomesYasuo Tsunaka0Hideaki Ohtomo1Yoshifumi Nishimura2Graduate School of Medical Life Science, Yokohama City UniversityGraduate School of Medical Life Science, Yokohama City UniversityGraduate School of Medical Life Science, Yokohama City UniversityNMR experiments reveal distinct interactions of the histone chaperone, FACT, with the proximal and distal flexible histone H2A and H2B tails of the asymmetrically unwrapped nucleosome.https://doi.org/10.1038/s42003-022-03785-z |
| spellingShingle | Yasuo Tsunaka Hideaki Ohtomo Yoshifumi Nishimura FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes Communications Biology |
| title | FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes |
| title_full | FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes |
| title_fullStr | FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes |
| title_full_unstemmed | FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes |
| title_short | FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes |
| title_sort | fact modulates the conformations of histone h2a and h2b n terminal tails within nucleosomes |
| url | https://doi.org/10.1038/s42003-022-03785-z |
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