Leveraging omics data to boost the power of genome-wide association studies

Summary: Genome-wide association studies (GWASs) have successfully identified many genetic variants and risk loci for complex traits and common diseases in the last 15 years. However, these identified variants, in general, can explain only a small to moderate proportion of the heritability, thus the...

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Bibliographic Details
Main Authors: Zhaotong Lin, Katherine A. Knutson, Wei Pan
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:HGG Advances
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247722000616