PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer

PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer

The identification of colorectal cancer (CRC) molecular targets is needed for the development of drugs that improve patient survival. We investigated the functional role of phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), a de novo purine...

Full description

Bibliographic Details
Main Authors: Sumit Agarwal, Balabhadrapatruni V. S. K. Chakravarthi, Michael Behring, Hyung-Gyoon Kim, Darshan S. Chandrashekar, Nirzari Gupta, Prachi Bajpai, Amr Elkholy, Sai A. H. Balasubramanya, Cherlene Hardy, Sameer Al Diffalha, Sooryanarayana Varambally, Upender Manne
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
colorectal cancer
paics
epithelial mesenchymal transition
mir-128
metastasis
jq1
Online Access:https://www.mdpi.com/2072-6694/12/4/772

Internet

https://www.mdpi.com/2072-6694/12/4/772

Similar Items