Modic type 2 changes are fibroinflammatory changes with complement system involvement adjacent to degenerated vertebral endplates

Modic type 2 changes are fibroinflammatory changes with complement system involvement adjacent to degenerated vertebral endplates

Abstract Background Vertebral endplate signal intensity changes visualized by magnetic resonance imaging termed Modic changes (MC) are highly prevalent in low back pain patients. Interconvertibility between the three MC subtypes (MC1, MC2, MC3) suggests different pathological stages. Histologically,...

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Bibliographic Details
Main Authors: Irina Heggli, Christoph J. Laux, Tamara Mengis, Agnieszka Karol, Frédéric Cornaz, Nick Herger, Borbala Aradi‐Vegh, Jonas Widmer, Marco D. Burkhard, Nadja A. Farshad‐Amacker, Sibylle Pfammatter, Witold E. Wolski, Florian Brunner, Oliver Distler, Mazda Farshad, Stefan Dudli
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:JOR Spine
Subjects:
degeneration
extracellular matrix
immune response
inflammation
Online Access:https://doi.org/10.1002/jsp2.1237

Internet

https://doi.org/10.1002/jsp2.1237

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