Transplantation of Skeletal Muscle-Derived Sca-1<sup>+</sup>/PW1<sup>+</sup>/Pax7<sup>−</sup> Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction

Transplantation of Skeletal Muscle-Derived Sca-1<sup>+</sup>/PW1<sup>+</sup>/Pax7<sup>−</sup> Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction

We have previously shown that skeletal muscle-derived Sca-1<sup>+</sup>/PW1<sup>+</sup>/Pax7<sup>−</sup> interstitial cells (PICs) are multi-potent and enhance endogenous repair and regeneration. Here, we investigated the regenerative potential of PICs following i...

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Bibliographic Details
Main Authors: Prashant J Ruchaya, Fiona C. Lewis-McDougall, Nitiphat Sornkarn, Sachin Amin, Benjamin Grimsdell, Abeer Shaalan, Guilia Gritti, Kyi Thar Soe, James E. Clark, Georgina M. Ellison-Hughes
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
skeletal muscle PW1<sup>+</sup>/Pax7<sup>−</sup> interstitial cells (PICs)
myocardial infarction
cardiac repair and regeneration
Online Access:https://www.mdpi.com/2073-4409/11/24/4050

Internet

https://www.mdpi.com/2073-4409/11/24/4050

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