Molecular effects of cardiac contractility modulation in patients with heart failure of ischemic aetiology uncovered by transcriptome analysis

Molecular effects of cardiac contractility modulation in patients with heart failure of ischemic aetiology uncovered by transcriptome analysis

Cardiac contractility modulation (CCM) is based on electrical stimulation of the heart without alteration of action potential and mechanical activation, the data on its fundamental molecular mechanisms are limited. Here we demonstrate clinical and physiological effect of 12 months CCM in 29 patients...

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Main Authors: E. Lyasnikova, K. Sukhareva, M. Vander, K. Zaitsev, M. Firulyova, A. Sergushichev, M. Sorokina, M. Trukshina, V. Galenko, T. Lelyavina, L. Mitrofanova, K. Simonova, M. Abramov, G. Faggian, G. B. Luciani, D. S. Lebedev, E. N. Mikhaylov, M. Sitnikova, A. Kostareva
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
CCM
autophagy
optimizer
heart failure
sarcomeric genes
RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1321005/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2024.1321005/full

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