Cell cycle-specific phosphorylation of p53 protein in A549 cells exposed to cisplatin and standardized air pollutants

Cell cycle-specific phosphorylation of p53 protein in A549 cells exposed to cisplatin and standardized air pollutants

Exposure to particulate matter is associated with DNA damage and the risk of lung cancer. Protein p53 is activated by multi-site phosphorylation in the early stages of DNA damage and affects cell outcome. Our study aimed to assess the effect of (100 µg/mL−1/24 h) standardized air pollutants: carbon...

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Bibliographic Details
Main Authors: Agata Niechoda, Katarzyna Milewska, Joanna Roslan, Karolina Ejsmont, Adam Holownia
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Physiology
Subjects:
A549
alveolar epithelial cells
cisplatin
DNA damage
nanoparticle carbon black
p53 phosphorylation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1238150/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1238150/full

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