Upregulation of proteolytic enzymes and cyclooxygenase-2 in human gingival fibroblasts stimulated with safrole
Background/purpose: Areca quid chewing is associated with periodontal diseases. Many of the undesirable effects of areca quid have been attributed to safrole, a major polyphenolic compound in the inflorescence of Piper betle. Matrix metalloproteinases (MMPs, a subclass of proteolytic enzymes), plasm...
Main Authors: | Yung-Chuan Ho, Ching-Chih Chen, Shun-Fa Yang, Fu-Mei Huang, Yu-Chao Chang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-03-01
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Series: | Journal of Dental Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S199179021300024X |
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