Exome Array Analysis of 9721 Ischemic Stroke Cases from the SiGN Consortium

Exome Array Analysis of 9721 Ischemic Stroke Cases from the SiGN Consortium

Recent genome wide association studies have identified 89 common genetic variants robustly associated with ischemic stroke and primarily located in non-coding regions. To evaluate the contribution of coding variants, which are mostly rare, we performed an exome array analysis on 106,101 SNPs for 972...

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Bibliographic Details
Main Authors: Huichun Xu, Kevin Nguyen, Brady J. Gaynor, Hua Ling, Wei Zhao, Patrick F. McArdle, Timothy D. O’Connor, O. Colin Stine, Kathleen A. Ryan, Megan Lynch, Jennifer A. Smith, Jessica D. Faul, Yao Hu, Jeffrey W. Haessler, Myriam Fornage, Charles Kooperberg, on behalf of the Trans-Omics for Precision Medicine (TOPMed) Stroke Working Group, James A. Perry, Charles C. Hong, John W. Cole, Elizabeth Pugh, Kimberly Doheny, Sharon L. R. Kardia, David R. Weir, Steven J. Kittner, Braxton D. Mitchell
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Genes
Subjects:
African American
exome wide association study
exome array
ischemic stroke
rare coding variants
Online Access:https://www.mdpi.com/2073-4425/14/1/61

Internet

https://www.mdpi.com/2073-4425/14/1/61

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