Extracellular signal-regulated kinases 1/2 as regulators of cardiac hypertrophy

Cardiac hypertrophy results from increased mechanical load on the heart and through the actions of local and systemic neuro-humoral factors, cytokines and growth factors. These mechanical and neuroendocrine effectors act through stretch, G protein-coupled receptors and tyrosine kinases to induce th...

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Bibliographic Details
Main Authors: Michael eMutlak, Izhak eKehat
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00149/full