Association of genetic and immuno-characteristics with clinical outcomes in patients with RET-rearranged non-small cell lung cancer: a retrospective multicenter study

Association of genetic and immuno-characteristics with clinical outcomes in patients with RET-rearranged non-small cell lung cancer: a retrospective multicenter study

Abstract Background Rearranged during transfection (RET) has been proven to be a tumorigenic target in non-small cell lung cancers (NSCLCs). In RET-rearranged NSCLCs, molecular features and their impact on prognosis were not well illustrated, and the activity of mainstay therapeutics has not current...

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Main Authors: Chang Lu, Xiao-Rong Dong, Jun Zhao, Xu-Chao Zhang, Hua-Jun Chen, Qing Zhou, Hai-Yan Tu, Xing-Hao Ai, Xiao-Feng Chen, Gai-Li An, Jun Bai, Jin-Lu Shan, Yi-Na Wang, Shuan-Ying Yang, Xiang Liu, Wu Zhuang, Hui-Ta Wu, Bo Zhu, Xue-Feng Xia, Rong-Rong Chen, De-Jian Gu, Hua-Min Xu, Yi-Long Wu, Jin-Ji Yang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Hematology & Oncology
Subjects:
Advanced NSCLC
RET rearrangement
Next-generationsequencing
TP53
Immune checkpoint inhibitor
Online Access:http://link.springer.com/article/10.1186/s13045-020-00866-6

Internet

http://link.springer.com/article/10.1186/s13045-020-00866-6

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