Exploring the interaction between extracellular matrix components in a 3D organoid disease model to replicate the pathophysiology of breast cancer

Exploring the interaction between extracellular matrix components in a 3D organoid disease model to replicate the pathophysiology of breast cancer

Abstract In vitro models are necessary to study the pathophysiology of the disease and the development of effective, tailored treatment methods owing to the complexity and heterogeneity of breast cancer and the large population affected by it. The cellular connections and tumor microenvironments obs...

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Bibliographic Details
Main Authors: Anamitra Bhattacharya, Kamare Alam, Nakka Sharmila Roy, Kulwinder Kaur, Santanu Kaity, Velayutham Ravichandiran, Subhadeep Roy
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
3D organoid
In-vitro disease model
Cell patterning
Tumor microenvironment
Extra cellular matrix
Cancer associated fibroblast
Online Access:https://doi.org/10.1186/s13046-023-02926-4

Internet

https://doi.org/10.1186/s13046-023-02926-4

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