Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation

Pranoprofen (PRA)-loaded nanostructured lipid carriers (NLC) have been dispersed into blank gels composed of 1% of Carbomer 940 (PRA-NLC-Car) and 3% of Sepigel<sup>®</sup> 305 (PRA-NLC-Sep) as a novel strategy to refine the biopharmaceutical profile of PRA, for dermal administration in t...

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Bibliographic Details
Main Authors: Negar Ahmadi, María Rincón, Marcelle Silva-Abreu, Lilian Sosa, Jessica Pesantez-Narvaez, Ana Cristina Calpena, María J. Rodríguez-Lagunas, Mireia Mallandrich
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/9/6/448