Delivery of therapeutic small interfering RNA: The current patent-based landscape

Implementing small interfering RNA (siRNA) is a promising therapy because it silences disease-related genes theoretically. However, the efficient delivery of siRNA is challenging, which limits its therapeutic applications. Various pharmaceutical delivery systems containing key technologies have been...

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Bibliographic Details
Main Authors: Yu Chen, Shi-Hang Xiong, Fei Li, Xiang-Jun Kong, De-Fang Ouyang, Ying Zheng, Hua Yu, Yuan-Jia Hu
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253122001639