Hyperuricemia exacerbates abdominal aortic aneurysm formation through the URAT1/ERK/MMP-9 signaling pathway

Hyperuricemia exacerbates abdominal aortic aneurysm formation through the URAT1/ERK/MMP-9 signaling pathway

Abstract Objective Previous studies have revealed associations between hyperuricemia and microvascular diseases, but the association between hyperuricemia and abdominal aortic aneurysm (AAA) remains unclear. The aim of this study was to elucidate the pathogenesis and prove the relationship between A...

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Bibliographic Details
Main Authors: Jen-Chun Wang, Shih-Hung Tsai, Hsiao-Ya Tsai, Shing-Jong Lin, Po-Hsun Huang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Cardiovascular Disorders
Subjects:
Hyperuricemia
Uric acid
Urate transporter 1
Matrix metalloproteinase
Abdominal aortic aneurysm
Online Access:https://doi.org/10.1186/s12872-022-03012-x

Internet

https://doi.org/10.1186/s12872-022-03012-x

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