Strategy and Performance Evaluation of Low-Frequency Variant Calling for SARS-CoV-2 Using Targeted Deep Illumina Sequencing

The ongoing COVID-19 pandemic, caused by SARS-CoV-2, constitutes a tremendous global health issue. Continuous monitoring of the virus has become a cornerstone to make rational decisions on implementing societal and sanitary measures to curtail the virus spread. Additionally, emerging SARS-CoV-2 vari...

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Bibliographic Details
Main Authors: Laura A. E. Van Poelvoorde, Thomas Delcourt, Wim Coucke, Philippe Herman, Sigrid C. J. De Keersmaecker, Xavier Saelens, Nancy H. C. Roosens, Kevin Vanneste
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.747458/full