Aggregation of Amyloidogenic Peptide Uperin—Molecular Dynamics Simulations

Uperin 3.5 is a remarkable natural peptide obtained from the skin of toadlets comprised of 17 amino acids which exhibits both antimicrobial and amyloidogenic properties. Molecular dynamics simulations were performed to study the β-aggregation process of uperin 3.5 as well as two of its mutants, in w...

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Bibliographic Details
Main Authors: Elena Ermakova, Olga Makshakova, Rauf Kurbanov, Ilya Ibraev, Yuriy Zuev, Igor Sedov
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/10/4070