The positive feedback loop of the NAT10/Mybbp1a/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I/R injury

The positive feedback loop of the NAT10/Mybbp1a/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I/R injury

Ferroptosis is a nonapoptotic form of regulated cell death that has been reported to play a central role in cardiac ischemia‒reperfusion (I/R) injury. N-acetyltransferase 10 (NAT10) contributes to cardiomyocyte apoptosis by functioning as an RNA ac4c acetyltransferase, but its role in cardiomyocyte...

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Bibliographic Details
Main Authors: Zhezhe Qu, Xiaochen Pang, Zhongting Mei, Ying Li, Yaozhi Zhang, Chuanhao Huang, Kuiwu Liu, Shuting Yu, Changhao Wang, Zhiyong Sun, Yingqi Liu, Xin Li, Yingqiong Jia, Yuechao Dong, Meixi Lu, Tiantian Ju, Fan Wu, Min Huang, Na Li, Shunkang Dou, Jianhao Jiang, Xianhui Dong, Yi Zhang, Wanhong Li, Baofeng Yang, Weijie Du
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Redox Biology
Subjects:
NAT10
ac4C
I/R injury
p53
Mybbp1a
Ferroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724001216

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http://www.sciencedirect.com/science/article/pii/S2213231724001216

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