EVALUATION OF THE CYTOTOXICITY AND GENOTOXICOLOGICAL SAFETY PROFILE OF BIOACTIVE SILVER(I) COMPLEXES WITH AMINOADAMANTANE LIGANDS

EVALUATION OF THE CYTOTOXICITY AND GENOTOXICOLOGICAL SAFETY PROFILE OF BIOACTIVE SILVER(I) COMPLEXES WITH AMINOADAMANTANE LIGANDS

Silver(I) complexes of amantadine (atdH), memantine (mtnH) and rimantadine (rtdH), named Ag-atd, Ag-mtn and Ag-rtd, respectively, were recently synthesized and described in the literature as promising antibacterial agents. In the present study, the cytotoxicity of such complexes was evaluated agains...

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Bibliographic Details
Main Authors: Igor Henrique Cerqueira, Maria Julia Mieli, Anna Karla dos Santos Pereira, Pedro Paulo Corbi, Flavia Aparecida Resende
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2024-03-01
Series:Química Nova
Subjects:
silver(I) complexes
antiproliferative activities
mutagenicity
Ames test
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422024000600201&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422024000600201&lng=en&tlng=en

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