miR-582 negatively regulates pre-B cell proliferation and survival through targeting Hif1α and Rictor
Abstract B cell development in bone marrow (BM) is a multi-staged process involving pro-B, pre-B, immature B, and mature B cells, among which pre-B cells undergo vigorous proliferation, differentiation, apoptosis, and gene rearrangement. While several signaling pathways participate in pre-B cell dev...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-02-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-04560-y |