miR-582 negatively regulates pre-B cell proliferation and survival through targeting Hif1α and Rictor

Abstract B cell development in bone marrow (BM) is a multi-staged process involving pro-B, pre-B, immature B, and mature B cells, among which pre-B cells undergo vigorous proliferation, differentiation, apoptosis, and gene rearrangement. While several signaling pathways participate in pre-B cell dev...

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Bibliographic Details
Main Authors: Xinxin Li, Yufei Zhang, Minhua Zheng, Xiuli Cao, Min Guo, Xiangyu Gao, Hua Han
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04560-y