MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

TRIM proteins are known to play critical roles in the context of viral infection. Here the authors establish MG53 (TRIM72) suppresses IFN and inflammation by modulation of ryanodine receptor related intracellular calcium induction.

Bibliographic Details
Main Authors: Matthew Sermersheim, Adam D. Kenney, Pei-Hui Lin, Temet M. McMichael, Chuanxi Cai, Kristyn Gumpper, T. M. Ayodele Adesanya, Haichang Li, Xinyu Zhou, Ki-Ho Park, Jacob S. Yount, Jianjie Ma
Format: Article
Language:English
Published: Nature Portfolio 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17177-6

Internet

https://doi.org/10.1038/s41467-020-17177-6

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