Endothelial colony forming cell administration promotes neurovascular unit development in growth restricted and appropriately grown fetal lambs

Endothelial colony forming cell administration promotes neurovascular unit development in growth restricted and appropriately grown fetal lambs

Abstract Background Fetal growth restriction (FGR) is associated with deficits in the developing brain, including neurovascular unit (NVU) dysfunction. Endothelial colony forming cells (ECFC) can mediate improved vascular stability, and have demonstrated potential to enhance vascular development and...

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Bibliographic Details
Main Authors: Alexander Bell, Ashalyn P. Watt, Ingrid Dudink, Yen Pham, Amy E. Sutherland, Beth J. Allison, Courtney A. McDonald, Margie Castillo-Melendez, Graham Jenkin, Atul Malhotra, Suzanne L. Miller, Tamara Yawno
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Stem Cell Research & Therapy
Subjects:
Brain injury
Blood brain barrier
Cord blood
Endothelial progenitor cells
ECFC
FGR
Online Access:https://doi.org/10.1186/s13287-023-03249-z

Internet

https://doi.org/10.1186/s13287-023-03249-z

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