Revisiting Telomere Shortening in Cancer
Telomeres, the protective structures of chromosome ends are gradually shortened by each cell division, eventually leading to senescence or apoptosis. Cancer cells maintain the telomere length for unlimited growth by telomerase reactivation or a recombination-based mechanism. Recent genome-wide analy...
Principais autores: | , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
MDPI AG
2019-01-01
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coleção: | Cells |
Assuntos: | |
Acesso em linha: | https://www.mdpi.com/2073-4409/8/2/107 |