Revisiting Telomere Shortening in Cancer

Telomeres, the protective structures of chromosome ends are gradually shortened by each cell division, eventually leading to senescence or apoptosis. Cancer cells maintain the telomere length for unlimited growth by telomerase reactivation or a recombination-based mechanism. Recent genome-wide analy...

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Detalhes bibliográficos
Principais autores: Keiji Okamoto, Hiroyuki Seimiya
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2019-01-01
coleção:Cells
Assuntos:
Acesso em linha:https://www.mdpi.com/2073-4409/8/2/107