Primary clear cell sarcoma of the femur: a unique case with RT-PCR and direct sequencing confirmation of EWSR1/ATF1 fusion gene

Primary clear cell sarcoma of the femur: a unique case with RT-PCR and direct sequencing confirmation of EWSR1/ATF1 fusion gene

Abstract Background It is very rare for clear cell sarcomas (CCS) to arise in the bone. During diagnosis, it is important to distinguish primary CCS of bone from bone metastasis of melanoma because this difference fundamentally changes the therapeutic options. Recently, characteristic fusion genes o...

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Bibliographic Details
Main Authors: Yuta Kubota, Kazuhiro Tanaka, Masanori Hisaoka, Tsutomu Daa, Tatsuya Iwasaki, Masanori Kawano, Ichiro Itonaga, Hiroshi Tsumura
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Musculoskeletal Disorders
Subjects:
Clear cell sarcoma
Primary bone tumor
Melanoma
Fusion gene
Direct sequencing
Reverse transcription polymerase chain reaction
Online Access:https://doi.org/10.1186/s12891-021-03969-4

Internet

https://doi.org/10.1186/s12891-021-03969-4

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