Quantitative MRI in early intervertebral disc degeneration: T1rho correlates better than T2 and ADC with biomechanics, histology and matrix content.

Low-back pain (LBP) has been correlated to the presence of intervertebral disc (IVD) degeneration on T2-weighted (T2w) MRI. It remains challenging, however, to accurately stage degenerative disc disease (DDD) based on T2w MRI and measurements of IVD height, particularly for early DDD. Several quanti...

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Bibliographic Details
Main Authors: Cornelis P L Paul, Theodoor H Smit, Magda de Graaf, Roderick M Holewijn, Arno Bisschop, Peter M van de Ven, Margriet G Mullender, Marco N Helder, Gustav J Strijkers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5790235?pdf=render