Heart failure induces significant changes in nuclear pore complex of human cardiomyocytes.

AIMS: The objectives of this study were to analyse the effect of heart failure (HF) on several proteins of nuclear pore complex (NPC) and their relationship with the human ventricular function. METHODS AND RESULTS: A total of 88 human heart samples from ischemic (ICM, n = 52) and dilated (DCM, n = 3...

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Main Authors: Estefanía Tarazón, Miguel Rivera, Esther Roselló-Lletí, Maria Micaela Molina-Navarro, Ignacio José Sánchez-Lázaro, Francisco España, José Anastasio Montero, Francisca Lago, José Ramón González-Juanatey, Manuel Portolés
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3495918?pdf=render