ML323 suppresses the progression of ovarian cancer via regulating USP1-mediated cell cycle

ML323 suppresses the progression of ovarian cancer via regulating USP1-mediated cell cycle

Background: Ubiquitin specific protease 1 (USP1) tightly correlates with poor prognosis of multiple cancers. However, whether USP1 underlies ovarian cancer (OV) progression remains unclarified.Methods: First, GSEA strategy and WGCNA analysis were used to screen for anti-ovarian cancer drugs and furt...

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Bibliographic Details
Main Authors: Baozhi Song, Yatao Jiang, Yu Jiang, Ying Lin, Jiahua Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genetics
Subjects:
ovarian cancer
ML323
deubiquitinase
USP1
cell cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.917481/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.917481/full

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