Nanomechanical mechanisms of Lyme disease spirochete motility enhancement in extracellular matrix

Nanomechanical mechanisms of Lyme disease spirochete motility enhancement in extracellular matrix

Martin Strnad, Yoo Jin Oh, and colleagues use single-molecule force spectroscopy and an extracellular matrix (ECM) analog that mimics natural tick feeding to show that the surface proteins DbpA/B can enhance spirochete motility in the ECM of the host. These results show that spirochetes can tune the...

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Bibliographic Details
Main Authors: Martin Strnad, Yoo Jin Oh, Marie Vancová, Lisa Hain, Jemiina Salo, Libor Grubhoffer, Jana Nebesářová, Jukka Hytönen, Peter Hinterdorfer, Ryan O. M. Rego
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01783-1

Internet

https://doi.org/10.1038/s42003-021-01783-1

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