Release of Iron-Loaded Ferritin in Sodium Iodate-Induced Model of Age Related Macular Degeneration: An In-Vitro and In-Vivo Study

Release of Iron-Loaded Ferritin in Sodium Iodate-Induced Model of Age Related Macular Degeneration: An In-Vitro and In-Vivo Study

In this report, we evaluated the role of iron in sodium iodate (NaIO<sub>3</sub>)-induced model of age-related macular degeneration (AMD) in ARPE-19 cells in-vitro, and mouse models in-vivo. ARPE-19 cells, a human retinal pigmented epithelial cell line, were exposed to 10 mM of NaIO<s...

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Bibliographic Details
Main Authors: Ajay Ashok, Suman Chaudhary, Aaron S. Wise, Neil A. Rana, Dallas McDonald, Alexander E. Kritikos, Ewald Lindner, Neena Singh
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antioxidants
Subjects:
ferritin
exosomes
age-related macular degeneration
lysosomes
sodium iodate
Online Access:https://www.mdpi.com/2076-3921/10/8/1253

Internet

https://www.mdpi.com/2076-3921/10/8/1253

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