Variations in <i>O</i>-Glycosylation Patterns Influence Viral Pathogenicity, Infectivity, and Transmissibility in SARS-CoV-2 Variants

Variations in <i>O</i>-Glycosylation Patterns Influence Viral Pathogenicity, Infectivity, and Transmissibility in SARS-CoV-2 Variants

The highly glycosylated S protein plays a vital role in host cell invasion, making it the principal target for vaccine development. Differences in mutations observed on the spike (S) protein of SARS-CoV-2 variants may result in distinct glycosylation patterns, thus influencing immunological evasion,...

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Bibliographic Details
Main Authors: Sherifdeen Onigbinde, Cristian D. Gutierrez Reyes, Mojibola Fowowe, Oluwatosin Daramola, Mojgan Atashi, Andrew I. Bennett, Yehia Mechref
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomolecules
Subjects:
SARS-CoV-2
mutations
<i>O</i>-glycosylation
pathogenicity
transmissibility
LC-MS/MS
Online Access:https://www.mdpi.com/2218-273X/13/10/1467

Internet

https://www.mdpi.com/2218-273X/13/10/1467

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