Mammalian genome evolution as a result of epigenetic regulation of transposable elements

Transposable elements (TEs) make up a large proportion of mammalian genomes and are a strong evolutionary force capable of rewiring regulatory networks and causing genome rearrangements. Additionally, there are many eukaryotic epigenetic defense mechanisms able to transcriptionally silence TEs. Furt...

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Bibliographic Details
Main Authors: Buckley Reuben M., Adelson David L.
Format: Article
Language:English
Published: De Gruyter 2014-06-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc-2014-0013