The anti-coagulants ASIS or APC do not protect against renal ischemia/ reperfusion injury

Renal ischemia/reperfusion (I/R) injury is the main cause of acute renal failure. The severity of injury is determined by endothelial damage as well as inflammatory and apoptotic processes. The anti-coagulants active site inhibited factor VIIa (ASIS) and activated protein C (APC) are besides their a...

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Bibliographic Details
Main Authors: Sarah Loubele, Arnold Spek, Peter Leenders, R A Matthijsen, Wim Buurman, carine peutz-kootstra, Hugo ten Cate, Henri Spronk
Format: Article
Language:English
Published: ScienceOpen 2014-05-01
Series:ScienceOpen Research
Online Access:https://www.scienceopen.com/document?vid=34421699-3b09-497d-bf20-61b35dfb919f