Identification of a novel regulatory pathway for PPARα by RNA-seq characterization of the endothelial cell lipid peroxidative injury transcriptome

Endothelial dysfunction caused by endothelial cell injuries is the initiating factor for atherosclerosis (AS), and lipid peroxidative injury is one of a dominant factor for AS pathogenesis. Using RNA-seq, we compared changes in transcriptome expression before and after endothelial cell injury, and f...

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Bibliographic Details
Main Authors: Fangfang Dou, Beiling Wu, Lin Sun, Jiulin Chen, Te Liu, Zhihua Yu, Chuan Chen
Format: Article
Language:English
Published: The Royal Society 2019-12-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190141