scifi-ATAC-seq: massive-scale single-cell chromatin accessibility sequencing using combinatorial fluidic indexing

scifi-ATAC-seq: massive-scale single-cell chromatin accessibility sequencing using combinatorial fluidic indexing

Abstract Single-cell ATAC-seq has emerged as a powerful approach for revealing candidate cis-regulatory elements genome-wide at cell-type resolution. However, current single-cell methods suffer from limited throughput and high costs. Here, we present a novel technique called scifi-ATAC-seq, single-c...

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Bibliographic Details
Main Authors: Xuan Zhang, Alexandre P. Marand, Haidong Yan, Robert J. Schmitz
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Genome Biology
Subjects:
Single-cell
ATAC-seq
Chromatin accessibility
Combinatorial fluidic indexing
Massive-scale
Online Access:https://doi.org/10.1186/s13059-024-03235-5

Internet

https://doi.org/10.1186/s13059-024-03235-5

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