Coordinated In Vitro Release of Granulysin, Perforin and IFN-γ in TB and HIV/TB Co-Infection Associated with Clinical Outcomes before and after Anti-TB Treatment

Granule-associated killing molecules released from cytotoxic T lymphocytes participate as a crucial step in immunity against tuberculosis (TB), but the role of coordinated production remains controversial. Coordinated release of effector molecules in vitro after stimulating peripheral blood mononucl...

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Bibliographic Details
Main Authors: Nada Pitabut, Panadda Dhepakson, Shinsaku Sakurada, Naoto Keicho, Srisin Khusmith
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/8/655