Modulation of soluble guanylate cyclase ameliorates pulmonary hypertension in a rat model of chronic thromboembolic pulmonary hypertension by stimulating angiogenesis

Abstract Acute pulmonary embolism (PE) does not always resolve after treatment and can progress to chronic thromboembolic disease (CTED) or the more severe chronic thromboembolic pulmonary hypertension (CTEPH). The mechanisms surrounding the likelihood of PE resolution or progress to CTED/CTEPH rema...

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Bibliographic Details
Main Authors: John Zagorski, Evandro Neto‐Neves, Nathan J. Alves, Amanda J. Fisher, Jeffrey A. Kline
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15156