Study of <i>MDM2</i> as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development Approach

Study of <i>MDM2</i> as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development Approach

An evaluation of the expression and predictive significance of the <i>MDM2</i> gene in brain lower-grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several transcriptome servers were used to measure the differential expression of the targeted <i>MDM2</...

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Bibliographic Details
Main Authors: Partha Biswas, Shabana Bibi, Qudsia Yousafi, Asim Mehmood, Shahzad Saleem, Awais Ihsan, Dipta Dey, Md. Nazmul Hasan Zilani, Md. Nazmul Hasan, Rasha Saleem, Aeshah A. Awaji, Usama A. Fahmy, Mohamed M. Abdel-Daim
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
<i>p53</i> gene
<i>MDM2</i> gene
onco-informatics
brain lower-grade glioma (LGG) cancer
predictive biomarker
Online Access:https://www.mdpi.com/1420-3049/28/7/2977

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https://www.mdpi.com/1420-3049/28/7/2977

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