Adaptive Natural Killer Cells Integrate Interleukin-18 during Target-Cell Encounter

Human cytomegalovirus (HCMV) infection induces adaptations in the natural killer (NK)-cell compartment. Expanded subsets of adaptive NK cells display potent effector functions against cellular targets, despite their apparent unresponsiveness to stimulation with classical dendritic cell-derived cytok...

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Bibliographic Details
Main Authors: Quirin Hammer, Timo Rückert, Josefine Dunst, Chiara Romagnani
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01976/full