Berberine activates macrophage autophagy and improves atherosclerotic plaque vulnerability

Berberine activates macrophage autophagy and improves atherosclerotic plaque vulnerability

Objective To explore the effect of berberine (BBR) on the vulnerability of atherosclerotic plaques caused by hyperglycemia and hyperlipidemia, and to discover the potential mechanism. Methods Male ApoE-/-mice were randomly divided into the control group, hyperglycemia group (intraperitoneal injectio...

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Bibliographic Details
Main Author: LIU Qin, YANG Li-xing, SHI Jing, HUANG Yu-qing, GAO Hong-ting, JU Rui, GUO Lei
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2020-05-01
Series:Jichu yixue yu linchuang
Subjects:
berberine|atherosclerotic plaque vulnerability|autophagy|nlrp3|mif
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200078.pdf

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http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200078.pdf

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