Construction, Structural Modeling of a Novel ScFv against Human Gastric Cancer from Phage-display Library

Using gastric cancer phage display library, a novel anti-human gastric cancer scFv, named as SC1 was screened. The SC1 gene was constructed and expressed in E.Coli. After sequencing, the heavy and light chain variable region of SC1 (named as SC1VH and SC1VL, respectively) was modeled using computer-...

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Bibliographic Details
Main Authors: Lijuan Yang, Haiyan Zhu, Bo Wei, Libo Yao, Chengzhi Su, Yiming Mu, Daxiang Cui
Format: Article
Language:English
Published: Tsinghua University Press 2011-03-01
Series:Nano Biomedicine and Engineering
Subjects:
Online Access:https://www.sciopen.com/article/10.5101/nbe.v3i1.p29-33