An integrated framework for prognosis prediction and drug response modeling in colorectal liver metastasis drug discovery

An integrated framework for prognosis prediction and drug response modeling in colorectal liver metastasis drug discovery

Abstract Background Colorectal cancer (CRC) is the third most prevalent cancer globally, and liver metastasis (CRLM) is the primary cause of death. Hence, it is essential to discover novel prognostic biomarkers and therapeutic drugs for CRLM. Methods This study developed two liver metastasis-associa...

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Bibliographic Details
Main Authors: Xiuman Zhou, Yuzhen Qian, Chen Ling, Zhuoying He, Peishang Shi, Yanfeng Gao, Xinghua Sui
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Subjects:
Colorectal liver metastasis
Prognostic biomarker
Deep learning
Drug sensitivity
Online Access:https://doi.org/10.1186/s12967-024-05127-5

Internet

https://doi.org/10.1186/s12967-024-05127-5

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