Linking metabolism and histone acetylation dynamics by integrated metabolic flux analysis of Acetyl-CoA and histone acetylation sites

Linking metabolism and histone acetylation dynamics by integrated metabolic flux analysis of Acetyl-CoA and histone acetylation sites

Objectives: Histone acetylation is an important epigenetic modification that regulates various biological processes and cell homeostasis. Acetyl-CoA, a hub molecule of metabolism, is the substrate for histone acetylation, thus linking metabolism with epigenetic regulation. However, still relatively...

Full description

Bibliographic Details
Main Authors: Anna-Sophia Egger, Eva Rauch, Suraj Sharma, Tobias Kipura, Madlen Hotze, Thomas Mair, Alina Hohenegg, Philipp Kobler, Ines Heiland, Marcel Kwiatkowski
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Molecular Metabolism
Subjects:
Metabolic flux analysis
Metabolism
Histone modifications
Epigenetics
LC-MS
Computational modelling
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824001637

Internet

http://www.sciencedirect.com/science/article/pii/S2212877824001637

Similar Items