Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans.

During cell division, the mitotic spindle segregates replicated chromosomes to opposite poles of the cell, while the position of the spindle determines the plane of cleavage. Spindle positioning and chromosome segregation depend on pulling forces on microtubules extending from the centrosomes to the...

Descrición completa

Detalles Bibliográficos
Main Authors: Vincent Portegijs, Lars-Eric Fielmich, Matilde Galli, Ruben Schmidt, Javier Muñoz, Tim van Mourik, Anna Akhmanova, Albert J R Heck, Mike Boxem, Sander van den Heuvel
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2016-10-01
Series:PLoS Genetics
Acceso en liña:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1006291&type=printable