Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed by RNA-Sequencing of B Lymphocytes

In addition to evolutionarily-accrued sequence mutation or deletion, endogenous retroelements (EREs) in eukaryotic genomes are subject to epigenetic silencing, preventing or reducing their transcription, particularly in the germplasm. Nevertheless, transcriptional activation of EREs, including endog...

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Main Authors: Jan Attig, George R. Young, Jonathan P. Stoye, George Kassiotis
פורמט: Article
שפה:English
יצא לאור: Frontiers Media S.A. 2017-12-01
סדרה:Frontiers in Microbiology
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גישה מקוונת:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02489/full