Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed by RNA-Sequencing of B Lymphocytes

In addition to evolutionarily-accrued sequence mutation or deletion, endogenous retroelements (EREs) in eukaryotic genomes are subject to epigenetic silencing, preventing or reducing their transcription, particularly in the germplasm. Nevertheless, transcriptional activation of EREs, including endog...

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Hlavní autoři: Jan Attig, George R. Young, Jonathan P. Stoye, George Kassiotis
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2017-12-01
Edice:Frontiers in Microbiology
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On-line přístup:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02489/full